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By David Dubnau (Eds.)

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67. Henner, D . , and Steinberg, W. (1979). J. Bacteriol. 139, 6 6 8 - 6 7 0 . 68. Higerd, T. B . (1977). J. Bacteriol. 129, 9 7 3 - 9 7 7 . 69. Higerd, T. B . , H o c h , J. Α . , and Spizizen, J. (1972). J. Bacteriol. 1026-1028. 70. H o c h , J. Α . , and Anagnostopoulos, C. (1970). J. Bacteriol. 103, 2 9 5 - 3 0 1 . 71. H o c h , J. Α . , and Coukoulis, J. H. (1978). J. Bacteriol. 133, 2 6 5 - 2 6 9 . 72. H o c h , J. Α . , and M a t h e w s , J. (1972). In "Spores V " (H. O. Halvorson, R. H a n s o n , and L.

In stationary-phase cells of B. subtilis, the c h r o m o s o m e is in a nearly c o m p l e t e d state of replication ( Y o s h i k a w a and S u e o k a , 1963a). , 1964). In their initial e x p e r i m e n t s , Y o s h i k a w a and S u e o k a (1963a) o b s e r v e d an ade-6 (purB6)lmet-5 (metB5) m a r k e r ratio of 2, indicating that replication p r o c e e d e d from an origin n e a r ade-6 to a terminus n e a r met-5. T h e s e results w e r e confirmed by following the sequential replication of m a r k e r s using the density transfer technique of M e s e l s o n and Stahl (1958).

Genetika (USSR) 10, 126-131. N e s t e r , E . W . , and Montoya, A . L. (1976). J. BacterioL 126, 6 9 9 - 7 0 5 . N e s t e r , E . W . , and Lederberg, J. (1963). Genetics 48, 5 2 9 - 5 5 1 . , Price, A . , Schack, L . , and T h o m a s s e n , E. (1978). Proc. Nat. Acad. Sei. USA 75, 1194-1198. Niaudet, B . , and Dedonder, R. (1975). Mol. Gen. Genet. 136, 3 3 7 - 3 4 9 . , and Maruo, Β. (1978). J. BacterioL 135, 8 1 8 - 8 2 1 . Oishi, M . , Oishi, Α . , and Sueoka, N . (1966). Proc. Nat. Acad.

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