Download Biology of Endothelial Cells by Eric A. Jaffe (auth.), Eric A. Jaffe (eds.) PDF

By Eric A. Jaffe (auth.), Eric A. Jaffe (eds.)

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In each ofthese cases, the appearance of a new tumor was correlated with an increase in migration stimulating activity relative to the postoperative levels. No significant activity was observed in the urine of patients with non-neoplastic disease or in the urine of healthy volunteers. Such results demonstrate that human tumors can be detected by measuring the response of capillary endothelial cells to tumor fluids. In addition to urine and ocular fluids, these assays may prove useful in detecting tumor-derived factors in cerebrospinal fluid, gastric and pancreatic secretions, sputum, ascites, and amniotic fluids.

7. F. S. 1951. Growth in vitro of blood vessels from bone marrow of adult chickens. Am. J. Anat. 89: 321-345. 8. C. M. 1953. The development of patent blood vessels from adult human rib marrow in tissue culture. Anat. Rec. 17: 663-683. 9. Maruyama, Y. 1963. The human endothelial cell in tissue culture. Z. Zellforsch 60: 69-79. 10. C. A. 1975. The isolation and culture of capillary endothelial cells from epididymal fat pad. Microvasc. Res. 10: 286-297. 11. J. W. 1981. Micropinocytosis of glycosylated albumin in microvessels: possible role in the pathogenesis of diabetes mellitus.

152: 931944. 57. E. A. 1980. y-glutamyl transpeptidase in isolated brain endothelial cell: induction by glial cells in vitro. Science 207: 653-655. 58. E. A. 1980. Induction of y-glutamyl transpeptidase in isolated cerebral endothelial cells. Advances in Experimental Medicine and Biology Series 131: 79-88. 59. Folkman, J. 1980. Angiogenesis in vitro. Nature 288: 551-556. 60. , Hyppa, T. R. 1980. Capillary endothelial cell migration: an in vitro assay method for aqueous humor. Surg. Forum xxxi: 498-500.

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