Download Mast Cells and Basophils by Gianni Marone, Lawrence M. Lichtenstein, Federica J. Galli PDF

By Gianni Marone, Lawrence M. Lichtenstein, Federica J. Galli

Mast Cells and Basophils should be crucial examining for immunologists, biochemists and scientific researchers. certain chapters hide all facets of mast cellphone and basophil study, from mobile improvement, proteases, histamine, cysteinyl leukotrienes, body structure and pathology to the function of those cells in well-being and affliction. Chapters additionally speak about the medical implications of histamine receptor antagonists.

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Gutierrez-Ramos Chapter 4 Regulation and Dysregulation of Mast Cell Survival and Apoptosis K. Hartmann and D. D. Metcalfe This Page Intentionally Left Blank CHAPTER 1 Regulation of Mast Cell and Basophil Development by Stem Cell Factor and Interleukin-3 M I N D Y TSAI, 1 CHRIS S. LANTZ 2 and STEPHEN J. A. INTRODUCTION In this chapter, we review current understanding of the effects of two cytokines, the c-kit ligand (or stem cell factor), and interleukin-3 (IL-3), on mast cell and basophil development, as well as review some of the effects of SCF on mast cell function.

32. 33. 34. 35. 36. 37. 38. 39. R E G U L A T I O N OF M A S T CELL AND B A S O P H I L D E V E L O P M E N T 15 the mouse and is the ligand for the c-kit tyrosine kinase receptor. Cell 63:213-224, 1990. Zsebo, K. , McNiece, I. , et al. Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver-conditioned medium. Cell 63:195-210, 1990. Besmer, E The kit ligand encoded at the murine Steel locus: a pleiotropic growth and differentiation factor.

Blood 87:2376-2385, 1996. Ihle, J. , et al. Biological properties of homogeneous interleukin 3. I. Demonstration of WEHI-3 growth factor activity, mast cell growth factor activity, P cell stimulating factor activity and histamine producing factor activity. J. Immunol. 131:282-287, 1983. 18 81. 82. 83. 84. 85. 86. 87. 88. 89. 90. 91. 92. 93. 94. 95. 96. 97. 98. 99. 100. 101. 102. 103. M I N D Y TSAI et al. Nabel, G. , Galli, S. , Dvorak, A. , Dvorak, H. E and Cantor, H. Inducer T lymphocytes synthesize a factor that stimulates proliferation of cloned mast cells.

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