Download Molecular Endocrinology by Franklyn Bolander (Auth.) PDF

By Franklyn Bolander (Auth.)

This textbook offers a historical past within the fundamentals of molecular endocrinology. a short precis of the sphere is equipped, while the rest of the textual content discusses the molecular elements of hormone motion in chronological order

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T h e latter p r e d o m i n a t e s , b u t b l o o d glucose levels d o n o t rise as m u c h as o n e w o u l d expect, b e c a u s e m u c h o f t h e glucose is oxidized. T r i i o d o t h y r o n i n e also stimu­ lates b o t h lipid synthesis a n d lipolysis; again, degradation p r e d o m i n a t e s . T h e s e effects o n lipolysis are b o t h direct a n d indirect; t h e latter actions are a result o f t h e potentiation o f t h e effects o f c a t e c h o l a m i n e s , G H , glucocorticoids, a n d glucagon.

General Endocrinology pins will b e secreted tonically. In h u m a n fetuses, s e r u m gonadotropin a n d testosterone levels return to b a s a l levels b y 2 8 w e e k s o f gestation a n d t h e testes will r e m a i n quiescent until puberty. In a d o l e s c e n c e , a n d r o g e n s h a v e important d e v e l o p m e n t a l , psychological, a n d sexual effects. A n d r o g e n s stimulate b o t h linear g r o w t h a n d skeletal m a t u ­ rity; that is, although the longitudinal g r o w t h o f b o n e s is accelerated, the growth plate shrinks a n d eventually b e c o m e s obliterated w h e n the e p i p h y s e s a n d diaphyses fuse.

W h e n the a n t r u m is c o m p l e t e , t h e entire structure is called a mature or Graafian follicle. V. Reproduction Primordial follicle 45 Oocyte G r a n u l o s a cells (squamous) Oocyte Primary follicle (early) Zona pellucida G r a n u l o s a cells (cuboidal) G r a n u l o s a cells (stratified) Primary follicle (late) Oocyte Zona pellucida Theca interna T h e c a externa Developing antrum Secondary follicle Theca interna Theca Oocyte Zona Theca pellucida externa interna Mature (Graafian) follicle Theca G r a n u l o s a cells externa G r a n u l o s a cells Oocyte Zona pellucida Fig.

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